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The Great Plague of London (1665-1666)
This description covers the Great Plague of London, which occurred between 1665 and 1666. During this time, the city of London was devastated by a deadly outbreak of bubonic plague, which killed an estimated 100,000 people. The plague was spread by rats and fleas, and the
From Wikipedia
The Great Plague of London, lasting from 1665 to 1666, was the most recent major epidemic of the bubonic plague to occur in England. It happened within the centuries-long Second Pandemic, a period of intermittent bubonic plague epidemics that originated in Central Asia in 1331, and included related diseases such as pneumonic plague and septicemic plague, which lasted until 1750.